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Contribution to current research

Image by Martin Adams

Research output enabled by ADTB samples

Published manuscripts 

 

2024

Stock AT, Parsons S, Hansen JA, D'Silva DB, Starkey G, Fayed A, Lim XY, D'Costa R, Gordon CL, Wicks IP. mTOR signalling controls the formation of smooth muscle cell-derived luminal myofibroblasts during vasculitis. EMBO Rep. 2024 Sep 13. doi: 10.1038/s44319-024-00251-1. Epub ahead of print. PMID: 39271773.

2023

Sharma VJ, Green A, McLean A, Adegoke J, Gordon CL, Starkey G, D'Costa R, James F, Afara I, Lal S, Wood B, Raman J. Towards a point-of-care multimodal spectroscopy instrument for the evaluation of human cardiac tissue. Heart Vessels. 2023 Aug 22. doi: 10.1007/s00380-023-02292-3. Epub ahead of print. PMID: 37608153.

Weeden CE, Gayevskiy V, Marceaux C, Batey D, Tan T, Yokote K, Ribera NT, Clatch A, Christo S, Teh CE, Mitchell AJ, Trussart M, Rankin L, Obers A, McDonald JA, Sutherland KD, Sharma VJ, Starkey G, D'Costa R, Antippa P, Leong T, Steinfort D, Irving L, Swanton C, Gordon CL, Mackay LK, Speed TP, Gray DHD, Asselin-Labat ML. Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer. Cancer Cell. 2023 May 8;41(5):837-852.e6. doi: 10.1016/j.ccell.2023.03.019. Epub 2023 Apr 21. PMID: 37086716.

Sharma V, Grant JAL, Gangahanumiah S, Singh A, Gordon CL, James F, D'Costa R, Starkey G, Raman J. Fresh human cardiac tissue for translational research: A novel method of sampling deceased organ donors. JTCVS Tech. 2023 Apr 17;19:77-79. doi: 10.1016/j.xjtc.2023.03.020. PMID: 37324328; PMCID: PMC10268497.

Sharma VJ, Adegoke JA, Afara IO, Stok K, Poon E, Gordon CL, Wood BR, Raman J. Near-infrared spectroscopy for structural bone assessment. Bone Jt Open. 2023 Apr 7;4(4):250-261. doi: 10.1302/2633-1462.44.BJO-2023-0014.R1. PMID: 37051828; PMCID: PMC10079377.

2022

Sharma VJ, Starkey G, D'Costa R, James F, Mouhtouris E, Davis L, Wang BZ, Vago A, Raman J, Mackay LK, Opdam H, Jones R, Grayson ML, Martin DE, Gordon CL. Australian Donation and Transplantation Biobank: A Research Biobank Integrated Within a Deceased Organ and Tissue Donation Program. Transplant Direct. 2022 Dec 12;9(1):e1422. doi: 10.1097/TXD.0000000000001422. PMID: 36591329; PMCID: PMC9750700.

Souter MNT, Awad W, Li S, Pediongco TJ, Meehan BS, Meehan LJ, Tian Z, Zhao Z, Wang H, Nelson A, Le Nours J, Khandokar Y, Praveena T, Wubben J, Lin J, Sullivan LC, Lovrecz GO, Mak JYW, Liu L, Kostenko L, Kedzierska K, Corbett AJ, Fairlie DP, Brooks AG, Gherardin NA, Uldrich AP, Chen Z, Rossjohn J, Godfrey DI, McCluskey J, Pellicci DG, Eckle SBG. CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells. J Exp Med. 2022 Sep 5;219(9):e20210828. doi: 10.1084/jem.20210828. Epub 2022 Aug 26. PMID: 36018322; PMCID: PMC9424912.

Stock AT, Parsons S, D'Silva DB, Hansen JA, Sharma VJ, James F, Starkey G, D'Costa R, Gordon CL, Wicks IP. Mechanistic Target of Rapamycin Inhibition Prevents Coronary Artery Remodeling in a Murine Model of Kawasaki Disease. Arthritis Rheumatol. 2022 Sep 3. doi: 10.1002/art.42340. Online ahead of print. PMID: 36057112

Stock AT, Parsons S, Sharma VJ, James F, Starkey G, D'Costa R, Gordon CL, Wicks IP. Intimal macrophages develop from circulating monocytes during vasculitis. Clin Transl Immunology. 2022 Aug 13;11(8):e1412. doi: 10.1002/cti2.1412. PMID: 35991774; PMCID: PMC9375838.

Tan HX, Juno JA, Esterbauer R, Kelly HG, Wragg KM, Konstandopoulos P, Alcantara S, Alvarado C, Jones R, Starkey G, Wang BZ, Yoshino O, Tiang T, Grayson ML, Opdam H, D'Costa R, Vago A; Austin Liver Transplant Perfusionist Group, Mackay LK, Gordon CL, Masopust D, Groom JR, Kent SJ, Wheatley AK. Lung-resident memory B cells established after pulmonary influenza infection display distinct transcriptional and phenotypic profiles. Sci Immunol. 2022 Jan 28;7(67):eabf5314. doi: 10.1126/sciimmunol.abf5314. Epub 2022 Jan 28. PMID: 35089815.

Alexandre YO, Schienstock D, Lee HJ, Gandolfo LC, Williams CG, Devi S, Pal B, Groom JR, Cao W, Christo SN, Gordon CL, Starkey G, D'Costa R, Mackay LK, Haque A, Ludewig B, Belz GT, Mueller SN. A diverse fibroblastic stromal cell landscape in the spleen directs tissue homeostasis and immunity. Sci Immunol. 2022 Jan 7;7(67):eabj0641. doi: 10.1126/sciimmunol.abj0641. Epub 2022 Jan 7. PMID: 34995096.

2021

Tan HX, Lee WS, Wragg KM, Nelson C, Esterbauer R, Kelly HG, Amarasena T, Jones R, Starkey G, Wang BZ, Yoshino O, Tiang T, Grayson ML, Opdam H, D'Costa R, Vago A; Austin Liver Transplant Perfusionist Group, Mackay LK, Gordon CL, Wheatley AK, Kent SJ, Juno JA. Adaptive immunity to human coronaviruses is widespread but low in magnitude. Clin Transl Immunology. 2021 Mar 17;10(3):e1264. doi: 10.1002/cti2.1264. PMID: 33747512; PMCID: PMC7968850.

Abstracts 

2024

Ali LA, et al. Development of a human intestinal organoid T cell co-culture model to study regulatory T cell functions. International Congress of Mucosal Immunology.

Deng J, et al. Immune system-microbe crosstalk is mediated by macrophage MR1 antigen presentation. CD1-MR1 International Conference.

Deng J, et al. Immune system-microbe crosstalk is mediated by macrophage MR1 antigen presentationAntigen Processing and Presentation Workshop.

Gordon CL. What happens after donation of samples to the ADTB? Victorian Donation and Transplantation Symposium.

Gordon CL. Biobanking and biorepositories – Translational opportunities (2024). ASID Clinical Research Network (CRN) Conference. 

Gordon CL. Establishing a Research Biobank in the context of donation for transplantation - managing information overload. Educational Workshop: Asking difficult questions during difficult times - Complex choices and practical challenges of consent. The Transplantation Society Conference.

Moe AAK, et al. Expression of P2X2 and P2X3 subunits in human post-mortem airway and vagal nerve samples. The 13th London International Cough Symposium.

Muraduzzaman AKM, et al. Do end-of-life events perturb the peptide landscape of transplant donor tissues? The 29th Annual Lorne Proteomics Symposium.
 

Muraduzzaman AKM, et al. Do end-of-life events perturb the peptide landscape of transplant donor tissues? The 37th European Immunogenetics & Histocompatibility Conference.

Sharma VJ, et al. Rapid multi-modal spectroscopy of fresh human cardiac tissue detects fibrosis in ischemic heart disease (IHD) and dilated cardiomyopathy (DCM). The 60th Annual Meeting of The Society of Thoracic Surgeons.

2023

Ali LA, et al. Beneficial effects of CD4+ Tregs on intestinal organoids. Immunology Group of Victoria (IgV) Annual Scientific Meeting.

Asselin-Labat ML, et al. Early immune pressure initiated by tissue-resident memory T cells sculpts tumour evolution in non-small cell lung cancer. Asia-Pacific Vaccine and Immunotherapy Congress.

Dini I, et al. ATLANTIS – ATLas of peptide ANtigens in Transplantable tISsues. 28th Annual Lorne Proteomics Symposium.

Field KR, et al. Pan-tissue analysis of adaptive immune responses. 10th International Gamma-Delta T Cell Conference.

Gordon CL. Australian Donation and Transplantation Biobank. Australasian Biobanking Network Association Annual Conference.

Sharma VJ, et al. Multimodal spectroscopic scans of cardiac tissue to diagnose myocardial fibrosis patterns in real time. The 59th Annual Meeting of The Society of Thoracic Surgeons.

Vicencio DM, et al. Exploring the distribution and phenotype of human γδ T cells across peripheral tissues. 10th International Gamma Delta T Cell Conference.

2022

Asselin-Labat ML, et al. Understanding tumour evolution using spatial multi-omics. Clinical Oncology Society of Australia 49th Annual Scientific Meeting.

Asselin-Labat ML, A graphical user interface to select FOVs on the MIBIscope. Spatial Biology – MIBI Workshop by Stanford University.

Clatch A, et al., Whole body analysis or tissue-resident immune cells. Australasia Society for Immunology IgV Scientific Meeting.

Field KR, et al., Anatomical distribution of human γδ T cell subsets. 50th Annual Scientific Meeting of the Australian and New Zealand Society for Immunology.

 

Gordon CL, Australian Donation and Transplantation Biobank. Melbourne Immunology Network (MIN) Reconnect Symposium.

Marceaux C, et al. Studying the immune microenvironment in lung cancer using spatial multi-omic approaches. Multi-Omics Inaugural Conference.

Moe AAK, et al. 3-dimensional mapping of neural innervation of human airways, Australasian Neuroscience Society 40th Annual Scientific Meeting.

 

2021

Clatch A, et al. Whole body analysis or tissue-resident immune cells. 8th Federation of Immunologists of Societies of Asia-Oceania.

 

Clatch A, et al. Whole body analysis or tissue-resident immune cells. 12th Biomed Link Conference.

Gordon CL, Human tissue-resident memory T cells in health and disease. 49th Annual Scientific Meeting of the Australian and New Zealand Society for Immunology.

Sharma VJ, et al. Australian Donation and Transplantation Biobank – First year of linking organ donation to scientific discovery. Royal Australasian College of Surgeons Annual Scientific Congress.

Sharma VJ, et al. Australian Donation and Transplantation Biobank – First year of linking organ donation to scientific discovery. Royal Australasian College of Surgeons Victorian Scientific Research Meeting.

2019

Gordon CL, et al. Establishing the Australian Transplantation Biobank. Connecting Donation and Transplantation: A decade of growth and collaboration.

Image by National Cancer Institute
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